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Article

Inconsistencies in estimating the age of HIV-1 subtypes due to heterotachy.

Molecular biology and evolution - 1 Feb 2012

Wertheim Joel O, Fourment Mathieu, Kosakovsky Pond Sergei L

Abstract excerpt

Rate heterogeneity among lineages is a common feature of molecular evolution, and it has long impeded our ability to accurately estimate the age of evolutionary divergence events. The development of relaxed molecular clocks, which model variable substitution rates among lineages, was intended to rectify this problem. Major subtypes of pandemic HIV-1 group M are thought to exemplify closely related lineages with...

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Identifiers

PMID: 22045998
DOI: 10.1093/molbev/msr266
PMCID: PMC3258043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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