Article
Dating the time of viral subtype divergence.
BMC evolutionary biology - 9 Jun 2008
O'Brien John D, She Zhen-Su, Suchard Marc A
Abstract excerpt
Precise dating of viral subtype divergence enables researchers to correlate divergence with geographic and demographic occurrences. When historical data are absent (that is, the overwhelming majority), viral sequence sampling on a time scale commensurate with the rate of substitution permits the inference of the times of subtype divergence. Currently, researchers use two strategies to approach this task, both...
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