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Article

A polymorphism within the connective tissue growth factor (CTGF) gene has no effect on non-invasive markers of beta-cell area and risk of type 2 diabetes.

Disease markers - 1 Jan 2011

Pivovarova Olga, Fisher Eva, Dudziak Katarzyna, Ilkavets Iryna, Dooley Steven, Slominsky Petr, Limborska Svetlana, Weickert Martin O, Spranger Joachim, Fritsche Andreas, Boeing Heiner, Pfeiffer Andreas F H, Rudovich Natalia

Abstract excerpt

Chromosomal locus 6q23 is strongly linked to type 2 diabetes (T2DM) and related features including insulin secretion in various ethnic populations. Connective tissue growth factor (CTGF) gene is an interesting T2DM candidate gene in this chromosome region. CTGF is a key mediator of progressive pancreatic fibrosis up-regulated in type 2 diabetes. In contrast, CTGF inactivation in mice compromises islet cell...

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Identifiers

PMID: 22045431
DOI: 10.3233/DMA-2011-0823
PMCID: PMC3826927

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A polymorphism within the connective tissue growth factor (CTGF) gene has no effect on non-invasive markers of beta-cell area and risk of type 2 diabetes.PMID 22045431Read ↗

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