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Article

Association of single nucleotide polymorphisms in IL-12 and IL-27 genes with colorectal cancer risk.

Clinical biochemistry - 1 Jan 2012

Huang Zhao-Quan, Wang Jun-Li, Pan Guo-Gang, Wei Ye-Sheng

Abstract excerpt

OBJECTIVES: Interleukin-12 (IL-12) plays an important role in antitumor immunity. Interleukin-27 (IL-27) is a novel IL-12 family member. The present studies demonstrate that IL-27 mediates potent antitumor activity. However, No studies have examined the association of these polymorphism with colorectal cancer (CRC). Therefore, we investigated the relationship of IL-12 and IL-27 gene polymorphisms and CRC. DESIGN...

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PMID: 22040814
DOI: 10.1016/j.clinbiochem.2011.10.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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