Article
Functional polymorphisms in the interleukin-12 gene contribute to cancer risk: evidence from a meta-analysis of 18 case-control studies.
Gene - 15 Nov 2012
Zhou Liping, Yao Fan, Luan Hong, Wang Yinling, Dong Xihua, Zhou Wenwen, Wang Qihui
Abstract excerpt
BACKGROUND: Emerging evidence from preclinical and clinical studies has shown that interleukin-12 (IL-12) has some effectiveness against endogenously arising carcinogenesis. Several potentially functional polymorphisms of IL-12 gene have been implicated in cancer risk, but individually published studies showed inconclusive results. The aim of this study was to investigate the association between IL-12...
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