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Article

Common genetic variants differentially influence the transition from clinically defined states of fasting glucose metabolism.

Diabetologia - 1 Feb 2012

Walford G A, Green T, Neale B, Isakova T, Rotter J I, Grant S F A, Fox C S, Pankow J S, Wilson J G, Meigs J B, Siscovick D S, Bowden D W, Daly M J, Florez J C

Abstract excerpt

AIMS/HYPOTHESIS: Common genetic variants have been associated with type 2 diabetes. We hypothesised that a subset of these variants may have different effects on the transition from normal fasting glucose (NFG) to impaired fasting glucose (IFG) than on that from IFG to diabetes. METHODS: We identified 16 type 2 diabetes risk variants from the Illumina Broad Candidate-gene Association Resource (CARe) array...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22038522
DOI: 10.1007/s00125-011-2353-8
PMCID: PMC3589986

Genes

GCK

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