Article
New insights into the performance of human whole-exome capture platforms.
Nucleic acids research - 23 Jun 2015
Meienberg Janine, Zerjavic Katja, Keller Irene, Okoniewski Michal, Patrignani Andrea, Ludin Katja, Xu Zhenyu, Steinmann Beat, Carrel Thierry, Röthlisberger Benno, Schlapbach Ralph, Bruggmann Rémy, Matyas Gabor
Abstract excerpt
Whole exome sequencing (WES) is increasingly used in research and diagnostics. WES users expect coverage of the entire coding region of known genes as well as sufficient read depth for the covered regions. It is, however, unknown which recent WES platform is most suitable to meet these expectations. We present insights into the performance of the most recent standard exome enrichment platforms from Agilent,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.