Article

Whole-genome sequencing is more powerful than whole-exome sequencing for detecting exome variants

2014-10-14

Abstract excerpt

We compared whole-exome sequencing (WES) and whole-genome sequencing (WGS) in six unrelated individuals. In the regions targeted by WES capture (81.5% of the consensus coding genome), the mean numbers of single-nucleotide variants (SNVs) and small insertions/deletions (indels) detected per sample were 84,192 and 13,325, respectively, for WES, and 84,968 and 12,702, respectively, for WGS. For both SNVs and indels,...

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Literature Corpus work: dacb4a6e-79ae-556b-85e8-9b261ec545c0
DOI: 10.1101/010363

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