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Article

Variant discovery in targeted resequencing using whole genome amplified DNA.

BMC genomics - 10 Jul 2013

Indap Amit R, Cole Regina, Runge Christina L, Marth Gabor T, Olivier Michael

Abstract excerpt

BACKGROUND: Next generation sequencing and advances in genomic enrichment technologies have enabled the discovery of the full spectrum of variants from common to rare alleles in the human population. The application of such technologies can be limited by the amount of DNA available. Whole genome amplification (WGA) can overcome such limitations. Here we investigate applicability of using WGA by comparing SNP and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23837845
DOI: 10.1186/1471-2164-14-468
PMCID: PMC3716764

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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