Article
Protein synthesis in yeast. Structural and functional analysis of the gene encoding elongation factor 3.
The Journal of biological chemistry - 15 Sept 1990
Sandbaken M G, Lupisella J A, DiDomenico B, Chakraburtty K
Abstract excerpt
The yeast translational elongation factor 3 (EF-3) stimulates EF-1 alpha-dependent binding of aminoacyl-tRNA by the ribosome. The requirement for EF-3 is unique to fungi; a functional analog has not been found in prokaryotes or other eukaryotes. We have isolated and characterized the structural gene, YEF3, that encodes EF-3. The YEF3 gene is present in one copy/haploid genome and is essential for vegetative...
Topics
- Amino Acid Sequence
- Aminoglycosides
- Anti-Bacterial Agents
- Base Sequence
- DNA, Fungal
- Fungal Proteins
- Genes, Fungal
- Genotype
- Molecular Sequence Data
- Peptide Elongation Factors
- Restriction Mapping