Article
The role of dam methyltransferase in the control of DNA replication in E. coli.
Cell - 7 Sept 1990
Boye E, Løbner-Olesen A
Abstract excerpt
The timing and control of initiation of DNA replication in E. coli was studied under conditions where the cellular level of dam methyltransferase was controlled by a temperature-inducible promoter. Flow cytometry was used to demonstrate that the synchrony of initiation at the several origins within each cell was critically dependent on the level of dam methyltransferase. Initiations were shown to be synchronous...
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