Article
Acid and base secretion in freshly excised nasal tissue from cystic fibrosis patients with ΔF508 mutation.
International forum of allergy & rhinology - 1 Jan 2000
Cho Do-Yeon, Hwang Peter H, Illek Beate, Fischer Horst
Abstract excerpt
BACKGROUND: Cystic fibrosis (CF) is caused by a misfunctional CF transmembrane conductance regulator (CFTR) protein, which is believed to contributes to the regulation of the airway surface liquid (ASL) pH. This study investigated acid and base secretion in freshly excised human nasal tissues from CF patients homozygous for the ΔF508 mutation. METHODS: Human nasal mucosa was collected during sinus surgery and...
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