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Article

Insights into the molecular determinants of EF-G catalyzed translocation.

RNA (New York, N.Y.) - 1 Dec 2011

Wang Leyi, Altman Roger B, Blanchard Scott C

Abstract excerpt

Translocation, the directional movement of transfer RNA (tRNA) and messenger RNA (mRNA) substrates on the ribosome during protein synthesis, is regulated by dynamic processes intrinsic to the translating particle. Using single-molecule fluorescence resonance energy transfer (smFRET) imaging, in combination with site-directed mutagenesis of the ribosome and tRNA substrates, we show that peptidyl-tRNA within the...

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Source

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Identifiers

PMID: 22033333
DOI: 10.1261/rna.029033.111
PMCID: PMC3222131

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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