Article
Lipid phenotype of two distinct subpopulations of Mycobacterium bovis Bacillus Calmette-Guerin Tokyo 172 substrain.
The Journal of biological chemistry - 23 Dec 2011
Naka Takashi, Maeda Shinji, Niki Mamiko, Ohara Naoya, Yamamoto Saburo, Yano Ikuya, Maeyama Jun-Ichi, Ogura Hisashi, Kobayashi Kazuo, Fujiwara Nagatoshi
Abstract excerpt
Bacillus Calmette-Guérin (BCG) Tokyo 172 is a predominant World Health Organization Reference Reagent for the BCG vaccine. Recently, the BCG Tokyo 172 substrain was reported to consist of two subpopulations with different colony morphologies, smooth and rough. Smooth colonies had a characteristic 22-bp deletion in Rv3405c of the region of difference (RD) 16 (type I), and rough colonies were complete in this...
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