Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional characterisation of three o-methyltransferases involved in the biosynthesis of phenolglycolipids in Mycobacterium tuberculosis.

PloS one - 1 Jan 2013

Simeone Roxane, Huet Gaëlle, Constant Patricia, Malaga Wladimir, Lemassu Anne, Laval Françoise, Daffé Mamadou, Guilhot Christophe, Chalut Christian

Abstract excerpt

Phenolic glycolipids are produced by a very limited number of slow-growing mycobacterial species, most of which are pathogen for humans. In Mycobacterium tuberculosis, the etiologic agent of tuberculosis, these molecules play a role in the pathogenicity by modulating the host immune response during infection. The major variant of phenolic glycolipids produced by M. tuberculosis, named PGL-tb, consists of a large...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Catalysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Order

Share to Glycolipids

Share to Methylation

Share to Methyltransferases

Share to Mycobacterium tuberculosis

Share to Sequence Alignment

Source

Open in PubMed Open full text

Identifiers

PMID: 23536839
DOI: 10.1371/journal.pone.0058954
PMCID: PMC3594219

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional characterisation of three o-methyltransferases involved in the biosynthesis of phenolglycolipids in Mycobacterium tuberculosis.PMID 23536839Read ↗

Characterization of three glycosyltransferases involved in the biosynthesis of the phenolic glycolipid antigens from the Mycobacterium tuberculosis complex.Semantic proximity Read ↗

Molecular dissection of the role of two methyltransferases in the biosynthesis of phenolglycolipids and phthiocerol dimycoserosate in the Mycobacterium tuberculosis complex.Semantic proximity Read ↗

A lipid profile typifies the Beijing strains of Mycobacterium tuberculosis: identification of a mutation responsible for a modification of the structures of phthiocerol dimycocerosates and phenolic glycolipids.Semantic proximity Read ↗

Trisaccharides of Phenolic Glycolipids Confer Advantages to Pathogenic Mycobacteria through Manipulation of Host-Cell Pattern-Recognition ReceptorsSemantic proximity Read ↗

Identification of a polyprenylphosphomannosyl synthase involved in the synthesis of mycobacterial mannosides.Semantic proximity Read ↗

Identification of the missing trans-acting enoyl reductase required for phthiocerol dimycocerosate and phenolglycolipid biosynthesis in Mycobacterium tuberculosis.Semantic proximity Read ↗

Underestimated Manipulative Roles of Mycobacterium tuberculosis Cell Envelope Glycolipids During InfectionSemantic proximity Read ↗

Both phthiocerol dimycocerosates and phenolic glycolipids are required for virulence of Mycobacterium marinum.Semantic proximity Read ↗

Targeting trehalose and methylglucose lipopolysaccharide biosynthetic pathways in M. tuberculosis : structural and functional characterisation, and early-stage drug discovery of OtsA and Rv3030Semantic proximity Read ↗

A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response.Semantic proximity Read ↗

The mycobacterial acyltransferase PapA5 is required for biosynthesis of cell wall-associated phenolic glycolipids.Semantic proximity Read ↗

Role of the pks15/1 Gene in the Biosynthesis of Phenolglycolipids in the Mycobacterium tuberculosisComplexSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.