Article
Inversion of thermosensing property of the bacterial receptor Tar by mutations in the second transmembrane region.
Journal of molecular biology - 12 Mar 1999
Nishiyama S, Maruyama I N, Homma M, Kawagishi I
Abstract excerpt
The aspartate chemoreceptor Tar of Escherichia coli serves as a warm sensor that produces attractant and repellent signals upon increases and decreases in temperature, respectively. However, increased levels of methylation of the cytoplasmic domain of Tar resulting from aspartate binding convert Tar to a cold sensor with the opposite signaling behavior. Detailed analyses of the methylation sites, which are...
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