Article
Mutational analysis of a transmembrane segment in a bacterial chemoreceptor.
Journal of bacteriology - 1 Aug 1996
Baumgartner J W, Hazelbauer G L
Abstract excerpt
Trg is a member of a family of receptors that mediates chemotaxis by Escherichia coli. Its transmembrane domain is a loose four-helix bundle consisting of two helices from each of the two identical subunits. This domain mediates transmembrane signaling through a conformational change in which the second transmembrane segment (TM2) is thought to move relative to TM1, but mutational analysis of TM2 by cysteine...
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