Article
Single nucleotide polymorphism upstream of interleukin 28B associated with phase 1 and phase 2 of early viral kinetics in patients infected with HCV genotype 1.
Journal of hepatology - 1 Mar 2012
Howell Charles D, Gorden Alexis, Ryan Kathleen A, Thompson Alexander J, Ibrahim Chadi, Fried Michael, Afdhal Nezam H, McHutchison John G, Shianna Kevin V, Goldstein David B, Shuldiner Alan R, Mitchell Braxton D
Abstract excerpt
BACKGROUND & AIMS: We studied the relationship between IL28B gene-related SNP rs12979860 and early viral kinetics (day 0-28) during peginterferon and ribavirin treatment, in 173 African Americans (AA) and 188 Caucasian Americans (CA) with HCV genotype 1. METHODS: We studied the relationship between IL28B 16 gene-related SNP rs12979860 and early viral kinetics (day 0-28) 17 during peginterferon and ribavirin...
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