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Article

Temperature-sensitive yeast mutants defective in mitochondrial inheritance.

The Journal of cell biology - 1 Sept 1990

McConnell S J, Stewart L C, Talin A, Yaffe M P

Abstract excerpt

The distribution of mitochondria to daughter cells is an essential feature of mitotic cell growth, yet the molecular mechanisms facilitating this mitochondrial inheritance are unknown. We have isolated mutants of Saccharomyces cerevisiae that are temperature-sensitive for the transfer of mitochondria into a growing bud. Two of these mutants contain single, recessive, nuclear mutations, mdm1 and mdm2, that cause...

Topics

Actins
Cell Cycle
Cell Division
Cell Nucleus
Cytoskeleton
Mitochondria
Mutation
Saccharomyces cerevisiae
Temperature
Tubulin
Vacuoles

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Identifiers

PMID: 2202739
DOI: 10.1083/jcb.111.3.967
PMCID: PMC2116285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2202739-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Temperature-sensitive yeast mutants defective in mitochondrial inheritance.PMID 2202739Read ↗

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