Article
Genome-wide profiling of blood pressure in adults and children.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2012
Taal Hendrik R, Verwoert Germaine C, Demirkan Ayse, Janssens A Cecile J W, Rice Kenneth, Ehret Georg, Smith Albert V, Verhaaren Ben F J, Witteman Jacqueline C M, Hofman Albert, Vernooij Meike W, Uitterlinden Andre G, Rivadeneira Fernando, Ikram M Arfan, Levy Daniel, van der Heijden Albert J, Jaddoe Vincent W V, van Duijn Cornelia M
Abstract excerpt
Hypertension is an important determinant of cardiovascular morbidity and mortality and has a substantial heritability, which is likely of polygenic origin. The aim of this study was to assess to what extent multiple common genetic variants contribute to blood pressure regulation in both adults and children and to assess overlap in variants between different age groups, using genome-wide profiling. Single...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.