Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A candidate gene analysis of methylphenidate response in attention-deficit/hyperactivity disorder.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Dec 2009

McGough James J, McCracken James T, Loo Sandra K, Manganiello Marc, Leung Michael C, Tietjens Jeremy R, Trinh Thao, Baweja Shilpa, Suddath Robert, Smalley Susan L, Hellemann Gerhard, Sugar Catherine A

Abstract excerpt

OBJECTIVE: This study examines the potential role of candidate genes in moderating treatment effects of methylphenidate (MPH) in attention-deficit/hyperactivity disorder (ADHD). METHOD: Eighty-two subjects with ADHD aged 6 to 17 years participated in a prospective, double-blind, placebo-controlled, multiple-dose, crossover titration trial of immediate release MPH three times daily. The subjects were assessed on a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Synaptosomal-Associated Protein 25
Share to Arousal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Central Nervous System Stimulants

Share to Cross-Over Studies

Share to Dopamine Plasma Membrane Transport Proteins

Share to Mathematics

Share to Methylphenidate

Share to Receptors, Dopamine D4

Source

Open in PubMed Open full text

Identifiers

PMID: 19858760
DOI: 10.1097/CHI.0b013e3181bc72e3
PMCID: PMC2888980

Genes

COMT
DRD4
SNAP25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A candidate gene analysis of methylphenidate response in attention-deficit/hyperactivity disorder.PMID 19858760Read ↗

Pharmacogenetic predictors of methylphenidate dose-response in attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

A candidate gene investigation of methylphenidate response in adult attention-deficit/hyperactivity disorder patients: results from a naturalistic study.Semantic proximity Read ↗

No significant association between genetic variants in 7 candidate genes and response to methylphenidate treatment in adult patients with ADHD.Semantic proximity Read ↗

Attention-deficit/hyperactivity disorder pharmacogenomics.Semantic proximity Read ↗

Pharmacogenetics of methylphenidate response and tolerability in attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

Genome-wide association study of response to methylphenidate in 187 children with attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

Integrative genomic analysis of methylphenidate response in attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

Pharmacogenetics predictors of methylphenidate efficacy in childhood ADHD.Semantic proximity Read ↗

Association analysis of norepinephrine transporter polymorphisms and methylphenidate response in ADHD patients.Semantic proximity Read ↗

The Association with Quantitative Response to Attention-Deficit/Hyperactivity Disorder Medication of the Previously Identified Neurodevelopmental Network Genes.Semantic proximity Read ↗

Candidate Gene Expression Investigation in Children With Attention Deficit Hyperactivity DisorderSemantic proximity Read ↗

Association of dopamine, serotonin, and nicotinic gene polymorphisms with methylphenidate response in ADHD.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.