Article
Site-specific mutagenesis of PRD1 DNA polymerase: mutations in highly conserved regions of the family B DNA polymerase.
Biochemical and biophysical research communications - 16 Aug 1990
Jung G H, Leavitt M C, Schultz M, Ito J
Abstract excerpt
The PRD1 DNA polymerase is a small multifunctional enzyme containing three major conserved amino acid sequences shared by family B DNA polymerases. Thus, the PRD1 DNA polymerase provides an useful model system with which to study structure-function relationships of DNA polymerase molecules. In or...
Topics
- Amino Acid Sequence
- Cloning, Molecular
- DNA-Directed DNA Polymerase
- Escherichia coli
- Molecular Sequence Data
- Mutation
- Plasmids