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Article

Scrutinizing Deleterious Nonsynonymous SNPs and Their Effect on Human POLD1 Gene.

Genetics research - 1 Jan 2022

Bappy Md Nazmul Islam, Roy Anindita, Rabbi Md Gulam Rabbany, Jahan Nusrat, Chowdhury Fahmida Akther, Hoque Syeda Farjana, Sajib Emran Hossain, Khan Parvez, Hossain Ferdaus Mohd Altaf, Zinnah Kazi Md Ali

Abstract excerpt

POLD1 (DNA polymerase delta 1, catalytic subunit) is a protein-coding gene that encodes the large catalytic subunit (POLD1/p125) of the DNA polymerase delta (Polδ) complex. The consequence of missense or nonsynonymous SNPs (nsSNPs), which occur in the coding region of a specific gene, is the replacement of single amino acid. It may also change the structure, stability, and/or functions of the protein. Mutation in...

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Identifiers

PMID: 35620275
DOI: 10.1155/2022/1740768
PMCID: PMC9117041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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