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Article

Enteric microbiome metabolites correlate with response to simvastatin treatment.

PloS one - 1 Jan 2011

Kaddurah-Daouk Rima, Baillie Rebecca A, Zhu Hongjie, Zeng Zhao-Bang, Wiest Michelle M, Nguyen Uyen Thao, Wojnoonski Katie, Watkins Steven M, Trupp Miles, Krauss Ronald M

Abstract excerpt

Although statins are widely prescribed medications, there remains considerable variability in therapeutic response. Genetics can explain only part of this variability. Metabolomics is a global biochemical approach that provides powerful tools for mapping pathways implicated in disease and in response to treatment. Metabolomics captures net interactions between genome, microbiome and the environment. In this...

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Identifiers

PMID: 22022402
DOI: 10.1371/journal.pone.0025482
PMCID: PMC3192752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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