Article
Dysfunctional telomeres in human BRCA2 mutated breast tumors and cell lines.
Mutation research - 3 Jan 2012
Bodvarsdottir Sigridur K, Steinarsdottir Margret, Bjarnason Hordur, Eyfjord Jorunn E
Abstract excerpt
In the present study the possible involvement of telomeres in chromosomal instability of breast tumors and cell lines from BRCA2 mutation carriers was examined. Breast tumors from BRCA2 mutation carriers showed significantly higher frequency of chromosome end-to-end fusions (CEFs) than tumors fro...
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