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Article

S100B gene polymorphisms predict prefrontal spatial function in both schizophrenia patients and healthy individuals.

Schizophrenia research - 1 Jan 2012

Zhai Jinguo, Cheng Lina, Dong Jicheng, Shen Qiuge, Zhang Qiumei, Chen Min, Gao Li, Chen Xiongying, Wang Keqin, Deng Xiaoxiang, Xu Zhansheng, Ji Feng, Liu Chuanxin, Li Jun, Dong Qi, Chen Chuansheng

Abstract excerpt

Animal studies have strongly implicated a role of S100B in spatial ability and our recent study of humans found that S100B gene polymorphisms (rs9722, rs1051169, and rs2839357) were associated with schizophrenia patients' spatial ability (as assessed by a block design task and a mental rotation task). In this study, we explored the associations between these and three additional SNPs in S100B and prefrontal...

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PMID: 22019077
DOI: 10.1016/j.schres.2011.09.029

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