Article
The effects of CACNA1C gene polymorphism on spatial working memory in both healthy controls and patients with schizophrenia or bipolar disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Feb 2012
Zhang Qiumei, Shen Qiuge, Xu Zhansheng, Chen Min, Cheng Lina, Zhai Jinguo, Gu Huang, Bao Xin, Chen Xiongying, Wang Keqin, Deng Xiaoxiang, Ji Feng, Liu Chuanxin, Li Jun, Dong Qi, Chen Chuansheng
Abstract excerpt
CACNA1C gene polymorphism (rs1006737) is a susceptibility factor for both schizophrenia (SCZ) and bipolar disorder (BP). However, its role in working memory, a cognitive function that is impaired in both diseases, is not clear. Using three samples, including healthy controls, patients with SCZ, and patients currently in manic episodes of BP, this study tested the association between the SNP rs1006737 and spatial...
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