Article
Glucose-induced activation of plasma membrane H(+)-ATPase in mutants of the yeast Saccharomyces cerevisiae affected in cAMP metabolism, cAMP-dependent protein phosphorylation and the initiation of glycolysis.
Biochimica et biophysica acta - 22 Jul 1992
dos Passos J B, Vanhalewyn M, Brandão R L, Castro I M, Nicoli J R, Thevelein J M
Abstract excerpt
Addition of glucose-related fermentable sugars or protonophores to derepressed cells of the yeast Saccharomyces cerevisiae causes a 3- to 4-fold activation of the plasma membrane H(+)-ATPase within a few minutes. These conditions are known to cause rapid increases in the cAMP level. In yeast strains carrying temperature-sensitive mutations in genes required for cAMP synthesis, incubation at the restrictive...
Topics
- Cell Membrane
- Cyclic AMP
- Enzyme Activation
- Fructose
- Fungal Proteins
- Glucose
- Glycolysis
- Kinetics
- Mutation
- Phosphorylation
- Proton-Translocating ATPases