Article
Relationship of endothelial nitric oxide synthase (eNOS) gene polymorphisms with diabetic retinopathy in Caucasians with type 2 diabetes.
Ophthalmic genetics - 1 Mar 2012
Santos Kátia G, Crispim Daisy, Canani Luís H, Ferrugem Paula T, Gross Jorge L, Roisenberg Israel
Abstract excerpt
BACKGROUND: Nitric oxide synthesized by endothelial nitric oxide synthase (eNOS) plays a key role in the regulation of endothelial function, and controversial results regarding the association of eNOS gene polymorphisms with diabetic complications have been reported. MATERIALS AND METHODS: In this case-control study, the relationship of the -786T/C, the VNTR intron 4 a/b and the 894G/T (Glu298Asp) polymorphisms...
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