Article
Association of VEGF and eNOS gene polymorphisms in type 2 diabetic retinopathy.
Molecular vision - 11 Apr 2006
Suganthalakshmi Balasubbu, Anand Rajendran, Kim Ramasamy, Mahalakshmi Rajendran, Karthikprakash Sundaramoorthi, Namperumalsamy Perumalsamy, Sundaresan Periasamy
Abstract excerpt
PURPOSE: Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis, and nitric oxide (NO) is an upstream and downstream regulator of VEGF mediated angiogenesis. VEGF and NO have been suggested to play an important role in the pathogenesis of microvascular complications in diabetic retinopathy (DR). The objective of this study was to examine the genetic variations of the VEGF and eNOS gene and...
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