Article
Association of eNOS gene polymorphisms with renal disease in Caucasians with type 2 diabetes.
Diabetes research and clinical practice - 1 Mar 2011
Santos Kátia G, Crispim Daisy, Canani Luís H, Ferrugem Paula T, Gross Jorge L, Roisenberg Israel
Abstract excerpt
AIM: In this study we investigated if the -786T>C, the VNTR intron 4 a/b and the 894G>T (Glu298Asp) polymorphisms in the eNOS gene were associated with renal disease in 617 type 2 diabetic Caucasian-Brazilians. These polymorphisms were also examined in 100 Caucasian healthy blood donors. METHODS: Genotyping of eNOS polymorphisms was performed by PCR or PCR-RFLP and haplotype frequencies were estimated using a...
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