Article
Genotype- and experience-dependent susceptibility to depressive-like responses in the forced-swimming test.
Psychopharmacology - 1 Nov 2002
Alcaro Antonio, Cabib Simona, Ventura Rossella, Puglisi-Allegra Stefano
Abstract excerpt
RATIONALE: The forced-swimming test (FST) is utilized to reproduce passive coping responses to stress that may model a relevant aspect of human depression in rodent species. Animals showing high levels of passive responses to the FST are assumed to model pathologically depressed individuals. OBJECTIVES: We evaluated sensitivity of FST-induced behavioral responses to the interaction between genetic and...
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