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Article

Effects of repeated maternal separation on anxiety- and depression-related phenotypes in different mouse strains.

Neuroscience and biobehavioral reviews - 1 Jan 2007

Millstein Rachel A, Holmes Andrew

Abstract excerpt

Genetic factors and early life adversity both play a major role in the etiology of mood and anxiety disorders. Previous studies have shown that postnatal maternal separation (MS) can produce lasting abnormalities in emotion-related behavior and neuroendocrine responses to stress in rodents. The present study sought to examine the effects of repeated MS in eight different inbred strains of mice (129S1/SvImJ,...

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Source

Identifiers

PMID: 16950513
DOI: 10.1016/j.neubiorev.2006.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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