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Article

Genetic testing for atherosclerosis risk: inevitability or pipe dream?

The Canadian journal of cardiology - 1 Nov 2008

Lanktree Matthew, Oh Jisun, Hegele Robert A

Abstract excerpt

Family history is a risk factor for coronary artery disease (CAD). However, defining this risk at the DNA level has been elusive. In 2007, four genome-wide association studies reported a strong association between CAD and a region on chromosome 9p21. The high-risk genotype was identified in up to 30% of individuals, creating the potential for a clinical genetic test to assist in the calculation of a patient's CAD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18987759
DOI: 10.1016/s0828-282x(08)70194-6
PMCID: PMC2644538

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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