Article
Translating genomic analyses into improved management of coronary artery disease.
Future cardiology - 1 Jul 2010
Johansen Christopher T, Lanktree Matthew B, Hegele Robert A
Abstract excerpt
Human genetic variation can modulate pathophysiologic processes that alter susceptibility to complex disease. Recent genomic analyses have sought to identify how common genetic variation alters susceptibility to coronary artery disease (CAD). From genome-wide association studies (GWAS), common genetic variants in several novel chromosomal loci have been associated with CAD. GWAS identified the 9p21 locus as the...
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