Article
TH17 deficiency in human disease.
The Journal of allergy and clinical immunology - 1 Jun 2012
McDonald Douglas R
Abstract excerpt
The differentiation of naive T cells into distinct subsets of effector T cells is critical for effective immunity against a wide variety of infectious agents in the environment. Activation of innate immune responses by Candida species through pattern-recognition receptors directs the subsequent development of naive T cells into T(H)17 cells, which are essential for effective mucosal immunity against fungi....
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