Article
Human genetic susceptibility to Candida infections.
Medical mycology - 1 Nov 2012
Plantinga Theo S, Johnson Melissa D, Scott William K, Joosten Leo A B, van der Meer Jos W M, Perfect John R, Kullberg Bart Jan, Netea Mihai G
Abstract excerpt
Infections with Candida spp. have different manifestations in humans, ranging from mucosal to bloodstream and deep-seated disseminated infections. Immunocompromised patients have increased susceptibility to these types of infections, due to reduced capacity to elicit effective innate or adaptive immunity. In addition, rare and common genetic variants in the human genome have been identified that influence...
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