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Article

Toll-like receptor 4 gene polymorphisms in polymyalgia rheumatica and elderly-onset rheumatoid arthritis.

Clinical and experimental rheumatology - 1 Jan 2000

Alvarez-Rodriguez Lorena, López-Hoyos Marcos, Beares Ignacio, Mata Cristina, Garcia-Unzueta Maite, Calvo-Alen Jaime, Blanco Ricardo, Aurrecoechea Elena, Tripathi Gaurav, Martinez-Taboada Victor Manuel

Abstract excerpt

OBJECTIVES: Coding variants in TLR4 gene have been reported to be associated with inflammatory diseases. The aim of this study was to determine whether two of these polymorphisms (Asp299Gly and Thr399Ile) of TLR4 contribute to the genetic background of polymyalgia rheumatica (PMR) and elderly-onset rheumatoid arthritis (EORA). Furthermore, we have attempted to correlate the functional consequences of these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22011399

Genes

TLR4

Provenance

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