Article
High levels of chromosome instability in polyploids of Saccharomyces cerevisiae.
Mutation research - 1 Aug 1990
Mayer V W, Aguilera A
Abstract excerpt
The yeast Saccharomyces cerevisiae was used to study the genetic consequences of polyploidy in a unicellular organism. Isogenic diploid (2N), triploid (3N) and tetraploid (4N) strains with a genetically marked chromosome VII (cyh2-leu1-CEN7-ade6) were constructed and were used to follow the loss of one, two or three chromosome VII's during mitosis. We found that as ploidy increased, the frequency of loss of a...
Topics
- Chromosomes, Fungal
- Diploidy
- Mitosis
- Mutation
- Polyploidy
- Saccharomyces cerevisiae