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Article

Association of CHRNA4 polymorphism with depression and loneliness in elderly males.

Genes, brain, and behavior - 1 Mar 2012

Tsai S-J, Yeh H-L, Hong C-J, Liou Y-J, Yang A C, Liu M-E, Hwang J-P

Abstract excerpt

The cholinergic receptor, nicotinic, alpha 4 (CHRNA4) gene encodes the neuronal nicotinic acetylcholine receptor alpha-4 subunit. Recent research has shown that a variation in CHRNA4 (rs1044396) affects attention and negative emotionality in normal adults. To determine the link between CHRNA4 variation and cognitive function/depressed mood, this study conducted a genotype-phenotype correlation analysis between...

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Source

Identifiers

PMID: 22008229
DOI: 10.1111/j.1601-183X.2011.00741.x

Genes

CHRNA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of CHRNA4 polymorphism with depression and loneliness in elderly males.PMID 22008229Read ↗

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