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Article

CHRNA7 polymorphisms and response to cholinesterase inhibitors in Alzheimer's disease.

PloS one - 1 Jan 2013

Weng Pei-Hsuan, Chen Jen-Hau, Chen Ta-Fu, Sun Yu, Wen Li-Li, Yip Ping-Keung, Chu Yi-Min, Chen Yen-Ching

Abstract excerpt

BACKGROUND: CHRNA7 encodes the α7 nicotinic acetylcholine receptor subunit, which is important to Alzheimer's disease (AD) pathogenesis and cholinergic neurotransmission. Previously, CHRNA7 polymorphisms have not been related to cholinesterase inhibitors (ChEI) response. METHODS: Mild to moderate AD patients received ChEIs were recruited from the neurology clinics of three teaching hospitals from 2007 to 2010 (n...

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Share to alpha7 Nicotinic Acetylcholine Receptor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 24391883
DOI: 10.1371/journal.pone.0084059
PMCID: PMC3877150

Genes

CHRNA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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