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Article

Receptor for activated protein C kinase 1 (RACK1) is overexpressed in papillary thyroid carcinoma.

Thyroid : official journal of the American Thyroid Association - 1 Nov 2011

Myklebust Line M, Akslen Lars A, Varhaug Jan Erik, Lillehaug Johan R

Abstract excerpt

BACKGROUND: The receptor for activated C kinase 1 (RACK1) has been shown to be overexpressed in several types of cancers such as breast, colon, melanomas, and lung. RACK1 is linked to Ras-Raf-mediated signal transduction and transformed foci formation of 3T3 cells in vitro, and since this pathway is central in papillary thyroid carcinoma (PTC) oncogenesis, we hypothesized that RACK1 could play a role in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Signal-Regulated MAP Kinases

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Source

Identifiers

PMID: 22007921
DOI: 10.1089/thy.2010.0186

Genes

RACK1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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