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Article

Mapping personal functional data to personal genomes.

Bioinformatics (Oxford, England) - 15 Dec 2011

Rivas-Astroza Marcelo, Xie Dan, Cao Xiaoyi, Zhong Sheng

Abstract excerpt

MOTIVATION: The sequencing of personal genomes enabled analysis of variation in transcription factor (TF) binding, chromatin structure and gene expression and indicated how they contribute to phenotypic variation. It is hypothesized that using the reference genome for mapping ChIP-seq or RNA-seq reads may introduce errors, especially at polymorphic genomic regions. RESULTS: We developed a Personal Genome Editor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22006915
DOI: 10.1093/bioinformatics/btr578
PMCID: PMC3232370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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