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Article

Personal genome sequencing: current approaches and challenges.

Genes & development - 1 Mar 2010

Snyder Michael, Du Jiang, Gerstein Mark

Abstract excerpt

The revolution in DNA sequencing technologies has now made it feasible to determine the genome sequences of many individuals; i.e., "personal genomes." Genome sequences of cells and tissues from both normal and disease states have been determined. Using current approaches, whole human genome sequences are not typically assembled and determined de novo, but, instead, variations relative to a reference sequence are...

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PMID: 20194435
DOI: 10.1101/gad.1864110
PMCID: PMC2827837

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