Genetic and epigenetic associations of circadian gene TIMELESS and breast cancer risk.

doi:10.1002/mc.20862

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Article

Genetic and epigenetic associations of circadian gene TIMELESS and breast cancer risk.

Molecular carcinogenesis - 1 Dec 2012

Fu Alan, Leaderer Derek, Zheng Tongzhang, Hoffman Aaron E, Stevens Richard G, Zhu Yong

Abstract excerpt

Results from recent molecular epidemiologic studies suggest that the core circadian genes play a role in breast tumorigenesis, possibly by influencing hormone regulation or other pathways relevant to cancer. In order to further evaluate this hypothesis, we conducted a genetic and epigenetic assoc...

Topics

Breast Neoplasms
Cell Cycle Proteins
Circadian Rhythm
Epigenesis, Genetic
Female
Genetic Predisposition to Disease
Genotype
Humans
Intracellular Signaling Peptides and Proteins
Polymorphism, Single Nucleotide

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