Article
Genetic and epigenetic associations of circadian gene TIMELESS and breast cancer risk.
Molecular carcinogenesis - 1 Dec 2012
Fu Alan, Leaderer Derek, Zheng Tongzhang, Hoffman Aaron E, Stevens Richard G, Zhu Yong
Abstract excerpt
Results from recent molecular epidemiologic studies suggest that the core circadian genes play a role in breast tumorigenesis, possibly by influencing hormone regulation or other pathways relevant to cancer. In order to further evaluate this hypothesis, we conducted a genetic and epigenetic association study of the circadian regulator TIMELESS in breast carcinogenesis. We detected significant associations between...
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