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Article

Expansion of Paneth Cell Population in Response to Enteric Salmonella enterica Serovar Typhimurium Infection

18 Oct 2011

Abstract excerpt

Paneth cells residing at the base of the small intestinal crypts contribute to the mucosal intestinal first line defense by secreting granules filled with antimicrobial polypeptides including lysozyme. These cells derive from the columnar intestinal stem cell located at position 0 and the transit amplifying cell located at position +4 in the crypts. We have previously shown that Salmonella enterica serovar...

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PMID: 22006567
DOI: 10.1128/iai.05638-11

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