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Article

Paneth Cell Alterations in the Development and Phenotype of Crohn's Disease.

Gastroenterology - 1 Feb 2017

Stappenbeck Thaddeus S, McGovern Dermot P B

Abstract excerpt

Pathogenesis of Crohn's disease (CD) involves immune and microbial dysregulation, induced by environmental factors in genetically susceptible individuals. There are believed to be multiple subtypes of CD, which contributes to its observed clinical heterogeneity. This concept has been reinforced by recognition of the complexity of the genetic, microbial, immune, and environmental factors that affect risk for CD....

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Identifiers

PMID: 27729212
DOI: 10.1053/j.gastro.2016.10.003
PMCID: PMC5209278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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