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Article

Distinct epithelial gene expression phenotypes in childhood respiratory allergy

17 Oct 2011

Abstract excerpt

Epithelial cell contribution to the natural history of childhood allergic respiratory disease remains poorly understood. Our aims were to identify epithelial pathways that are dysregulated in different phenotypes of respiratory allergy. We established gene expression signatures of nasal brushings from children with dust mite-allergic rhinitis, associated or not associated with controlled or uncontrolled asthma....

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PMID: 22005912
DOI: 10.1183/09031936.00070511

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