Article

Nasal IFN and UPR Transcriptomic Signatures Complement Clinical Predictors of Frequent Exacerbations in Pediatric Asthma

2026-02-05

Abstract excerpt

<h4>Background: </h4> Frequent exacerbations in pediatric asthma cause substantial morbidity, yet tools for prospective risk stratification remain limited. We aimed to identify nasal transcriptomic signatures associated with frequent exacerbations (FE), test their virus responsiveness, and compare their predictive performance with a model based on routine clinical variables. <h4>Methods:</h4> Nasal RNA-seq data fr...

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Literature Corpus work: 85e34ea0-d526-5c0e-9d38-20c59a48f0ce
DOI: 10.22541/au.177028044.40839935/v1

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