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Article

Heme oxygenase-1 inhibits progression and destabilization of vulnerable plaques in a rabbit model of atherosclerosis.

European journal of pharmacology - 15 Dec 2011

Li Tingting, Tian Hongbo, Zhao Yuxia, An Fengshuang, Zhang Lei, Zhang Jianning, Peng Jie, Zhang Yun, Guo Yuan

Abstract excerpt

Although heme oxygenase-1 (HO-1) has been implicated in protection against atherogenesis, its role in vulnerable plaques remains to be fully elucidated. This study was aimed to explore the effect of HO-1 on the progression and stabilization of vulnerable plaques and the possible mechanism. We established a vulnerable plaque model by local transfection with recombinant p53 adenovirus to plaques in rabbits fed a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Nitric Oxide

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Source

Identifiers

PMID: 22004613
DOI: 10.1016/j.ejphar.2011.09.188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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